Publications

Selected Publications

You can also find my articles on my Google Scholar profile.

Journal Articles

The Optically Guided and Pre-assembled Implantation Cranial Window Reveals Cortical Spatial Representations during Navigation

The Optically Guided and Pre-assembled Implantation Cranial Window Reveals Cortical Spatial Representations during Navigation

Weihao Zhao; Lin Gao; Yu Wu; Guihua Xiao; Angran Li; Mingrui Wang; Hongyu Liu; Jinyuan Yang; Dongyue Jin; Yuanlong Zhang; Yongyi Yuan; Pu Dai

Research 2026

Head-mounted miniaturized microscopes have provided new capabilities for neuroscience by enabling neural imaging in freely behaving animals. The long-term application of these microscopes, however, is contingent upon sp…

A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice

A miniaturized mesoscope for the large-scale single-neuron-resolved imaging of neuronal activity in freely behaving mice

Yuanlong Zhang; Lekang Yuan; Qiyu Zhu; Jiamin Wu; Tobias Nöbauer; Rujin Zhang; Guihua Xiao; Mingrui Wang; Hao Xie; Zengcai Guo; Qionghai Dai; Alipasha Vaziri

Nature Biomedical Engineering 2024

Exploring the relationship between neuronal dynamics and ethologically relevant behaviour involves recording neuronal-population activity using technologies that are compatible with unrestricted animal behaviour. Howeve…

Real-time denoising enables high-sensitivity fluorescence time-lapse imaging beyond the shot-noise limit

Real-time denoising enables high-sensitivity fluorescence time-lapse imaging beyond the shot-noise limit

Xinyang Li; Yixing Li; Yilaing Zhou; Jiamin Wu; Zhifeng Zhao; Jiaqi Fan; Fei Deng; Zhaofa Wu; Guihua Xiao; Jing He; Yuanlong Zhang; Guoxun Zhang; Xiaowan Hu; Xingye Chen; Yi Zhang; Hui Qiao; Hao Xie; Yulong Li; Haoqian Wang; Lu Fang; Qionghai Dai

Nat Biotechnol 2022

A fundamental challenge in fluorescence microscopy is the photon shot noise arising from the inevitable stochasticity of photon detection. Noise increases measurement uncertainty and limits imaging resolution, speed and…

Conference Papers